Tag: 3D printing

A Functional, Beating Hearts Will Soon Be 3D-Printed Using Patients’ Own Cells

Inside a lab that will open in a couple of months in Chicago, a biotech startup will soon begin perfecting the process of 3D-printing human hearts that could eventually be used in transplants.

The process combines several steps that have been developed by various researchers in university labs. First, a patient’s heart will be scanned using an MRI machine to create a digital image of the heart’s shape and size.

Next, doctors will take a blood sample. Using techniques that have been developed over the last decade, the blood cells will be converted into stem cells–and then converted a second time into heart cells.

Those new heart cells will be combined with nutrients in a hydrogel to make a “bio-ink” that can be used in a specialized 3D printer.

Printing one layer at a time, with a biodegradable scaffolding to keep everything in place, the cells can be formed into the exact shape of the patient’s original heart.

The new heart will be moved to a bioreactor to strengthen it. Amazingly, new heart cells outside a body will begin to self-assemble.

When the heart is strong enough, technicians will raise the temperature to melt the scaffolding around the cells.




The new heart can then be transplanted–and because it is the exact size of a patient’s original heart, and made from the patient’s own cells, it has a greater chance of success than a traditional transplant.

In studies, other researchers have successfully transplanted stem cells in both humans and animals without the need for anti-rejection drugs.

Most people who receive heart transplants now don’t live more than a decade. Their body may reject the organ directly.

The drugs they take to suppress their immune system–in an attempt to prevent the body from rejecting the foreign organ–may also make them unable to fight off another disease, such as cancer.

The Biolife4D heart, in contrast, won’t require patients to take immunosuppressant drugs since it is an exact genetic match.

The company isn’t the only startup in the space. A startup called Prellis Biologics, for example, has another printing process that is optimized for speed, and that includes blood vessels.

A company called Organovo already makes 3D printed human tissue for drug discovery. But Biolife4D may be the only startup to use equity crowdfunding.

The company has opened up investment to the public. “We wanted to make [the investment opportunity] available to everybody, not just wealthy people on Wall Street,” Morris says.

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Pass it on: New Scientist

Nike’s Vaporfly Elite FlyPrint Leans Hard Into Computational Design

Computational design is the hottest phrase in manufacturing and 3D printing at the moment.

It’s changing the way people make all kinds of goods, and Nike used it to design and manufacture its new Vaporfly Elite FlyPrint shoe, which it’s announcing today.

The shoe is a specialized edition of its Zoom Vaporfly Elite 4%, which was used by elite runner Eliud Kipchoge during Nike’s Breaking2 event, which resulted in the fastest marathon ever run.

The special sauce in this edition is the FlyPrint upper, which is printed on the fly by a specially customized 3D printer out of a proprietary Nike polymer.

The material is printed out in a pattern specifically designed for a given athlete’s needs and attached to the much hyped Zoom X foam midsole from the 4% model.

The process, which Nike is calling FlyPrint, has some similarities to Nike’s other famous ‘fly’ process, FlyKnit, hence the name. The printing process, says Chen, is a lot like painting the material.

The uppers look a lot like a regular butterfly upper, with the same kind of flexibility you’re used to seeing from fabric or other polymer-based upper materials. This is not a hard-shell 3D-printed material, it’s a fabric of sorts.




This is reinforced by the fact that several components of the shoe are still made of FlyKnit including the tongue and collar. Those parts are so similar in chemical composition that there is no glue needed to attach them.

Instead, the FlyPrint material is bonded seamlessly with the FlyKnit, making for a one-piece design that is stronger and lighter.

The process of computer aided design in consumer products has a long history — but computational design is an evolution of this concept and has begun to gain steam lately with production-ready 3D-printing processes like Carbon’s

Carbon’s M-series digital light synthesis printers and Desktop Metal’s Production System.

The guiding force behind computational design is that you feed parameters and physical properties into a model — basically limitations and desired outcomes — and get designs that would either be impossible or incredibly time consuming for humans to produce.

In the case of the new FlyPrint upper, the constraints are the properties of the material and the forces that Kipchoge’s feet were exerting on that material.

With that data, along with the chemical composition of the polymer, a computational model allowed Nike to tweak the design for support, flexibility, reinforcement or relaxation on a much more granular level than they could ever accomplish with FlyKnit.

Nike is using an established 3D printing process called fused deposition modeling, basically painting shapes onto a surface with production-ready TPU materials.

Neither will say what printers Nike is using but note the company’s history in ‘hacking’ manufacturing tools to get the job done. As an industry note, Stratasys is one of the more established players in FDM printing.

Computational design and production ready 3D printing are changing footwear as we speak. Adidas and Carbon are focusing on the midsole in fashion and basketball, Nike is reinventing the upper for elite runners.

But the real gem here might not be the speed or customization — both important advancements.

The Vaporfly Elite FlyPrint is a product for elite runners only, and a small amount of them will be available at an event in London soon, as well as on the feet of Kipchoge and other Nike runners.

But there is an epochal shift in the way shoes (and other products) are made coming, and this is one of the harbingers of that shift. Pay attention.

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Pass it on: Popular Science

3D Printing, AI, and The Future of Design With Greg Porter from Greg’s Garage

Greg Porter is an architect, designer, maker and the host of the YouTube channel Greg’s Garage, where he builds cool designs and solutions using 3D printing and fabrication machines that he built with his own hands.

In this interview, we talk about his journey to being an architect, what moves him as a maker and designer, and the future of design as we integrate our creativity with artificial intelligence.

You can find more about Greg on his website, www.gregsgaragekc.com.

You can also subscribe to his YouTube channel at https://www.youtube.com/channel/UCPy-ulK_kHKVnSmb62uOncg